Cefotaxime is an antibiotic used to treat a large number of bacterial infections. It is on the World Health Organization’s List of Essential Medicines. WynSep therefore developed an analytical strategy based on capillary electrophoresis separation to control Cefotaxime concentration in the preparation before injecting the patients. The developed method appears as rapid and accurate.
L'avis de l'expert : Example of the CE use for quality control of pharmaceutical preparations.
Réactifs et conditions d'analyse
Tampon : Phosphate
Capillaire : bare-fused silica, L = 50 cm, ID = 50 μm
Injection : hydrodynamic, 50 mbar, 5 s
Tension : +25 kV
Détection : UV, 254 nm
Température : 25 °C