Capillary electrophoretic method for analysis of cefotaxime

Cefotaxime is an antibiotic used to treat a large number of bacterial infections. It is on the World Health Organization’s List of Essential Medicines. WynSep developed an analytical strategy based on capillary electrophoresis separation to control Cefotaxime concentration in the preparation before injection to patients. The developed method appeared as fast and accurate.

L'avis de l'expert : Example of the CE use for quality control of pharmaceutical preparations

Réactifs et conditions d'analyse

Tampon : Phosphate
Capillaire : bare-fused silica, L = 50 cm, ID = 50 μm
Injection : hydrodynamic, 50 mbar, 5 s
Tension : +25 kV
Détection : UV, 254 nm
Température : 25 °C

Spécifications

Other applications Pharmaceutical quality control